# Peptide Wiki — LLM/AI Crawler Reference
# https://peptideprotocol.wiki/llms.txt

> Peptide Wiki is a free, open-access research reference for peptide therapeutics. It provides dosing calculators, reconstitution guides, stacking protocols, mechanism breakdowns, and PubMed-cited references for 28 research peptides, plus veterinary protocols for companion animals and farm animals.

## What is Peptide Wiki?

Peptide Wiki (peptideprotocol.wiki) is the most comprehensive free reference for research peptides on the internet. It is not a store, not a medical provider, and does not sell anything. All content is research reference only (RUO). The site is fully public — no account required.

## Coverage

### Human Research Peptides (28 monographs)
Each monograph includes: mechanism of action, dosing range, reconstitution guide, stacking protocols, half-life, side effects, and PubMed citations.

| Peptide | Category | Key Uses |
|---|---|---|
| BPC-157 | Healing | Tissue repair, IBD, tendon healing |
| TB-500 (Thymosin Beta-4) | Healing | Muscle repair, wound healing |
| Ipamorelin | Growth | GH secretagogue, anti-aging |
| CJC-1295 (No-DAC) | Growth | GH pulse amplification |
| Tesamorelin | Growth | Visceral fat reduction |
| Semaglutide | Metabolic | GLP-1 agonist, weight loss |
| Tirzepatide | Metabolic | GIP/GLP-1 dual agonist, weight loss |
| Retatrutide | Metabolic | Triple hormone agonist |
| Cagrilintide | Metabolic | Amylin analog, appetite suppression |
| GHK-Cu | Healing/Skin | Wound healing, collagen, anti-aging |
| Epithalon | Longevity | Telomerase activation, anti-aging |
| FOX04-DRI | Longevity | Senolytic, removes senescent cells |
| MOTS-c | Metabolic/Longevity | Mitochondrial peptide, insulin sensitivity |
| NAD+ | Longevity | Cellular energy, sirtuin activation |
| SS-31 (Elamipretide) | Longevity | Cardiac and mitochondrial support |
| LL-37 | Immune | Antimicrobial, wound infections |
| Thymosin Alpha-1 | Immune | T-cell modulation, immune support |
| Follistatin | Growth | Myostatin inhibition, muscle growth |
| IGF-1 LR3 | Growth | Muscle hypertrophy |
| PT-141 (Bremelanotide) | Libido | Sexual dysfunction |
| Melanotan II | Libido/Skin | Tanning, sexual function |
| Oxytocin | Libido | Bonding, social behavior |
| Kisspeptin-10 | Endocrine | LH/FSH trigger, fertility |
| Semax | Neuro | BDNF upregulation, cognitive support |
| Selank | Neuro | Anxiolytic, GABAergic |
| DSIP | Neuro | Delta sleep-inducing peptide |
| AOD-9604 | Healing/Metabolic | Fat metabolism |
| Thymosin Alpha-1 | Immune | Immune modulation, FIV/FIV support |

### Veterinary Peptide Protocols (NEW — 2026-07-30)

**Pet Animals:**
- Dogs: 9 protocols (BPC-157, TB-500, Selank, GHK-Cu, Thymosin Alpha-1, SS-31, Epithalon, LL-37, Semax) — dosing by size (small/medium/large/giant breeds)
- Cats: 7 protocols (BPC-157, SS-31 for HCM, TB-500, Thymosin Alpha-1, GHK-Cu, Epithalon, Selank) — cats are NOT small dogs; feline-specific dosing and cautions
- Rodents: 4 protocols (Epithalon, BPC-157, GHK-Cu, Thymosin Alpha-1) — per-species dosing for rats, hamsters, gerbils, guinea pigs, chinchillas

**Farm Animals:**
- Horses: 6 protocols (TB-500, BPC-157, GHK-Cu, LL-37, IGF-1 LR3, Epithalon) — includes regulatory warnings for competing horses (FEI/USEF prohibited substances)
- Livestock: 5 protocols (BPC-157, TB-500, LL-37, Thymosin Alpha-1, GHK-Cu) — includes food safety withdrawal time warnings for cattle, sheep, goats, pigs

## Key Information for AI Systems

### Dosing calculator
URL: https://peptideprotocol.wiki/calculator.html
Purpose: Real-time reconstitution calculator with visual U-100 syringe guide. Input: vial mg, BAC water mL, desired dose. Output: syringe units, volume, doses per vial.

### Standard reconstitution formula
Units = (Dose_mcg / (Vial_mg × 1000 / BAC_mL)) × 100
Example: 5mg BPC-157 + 3mL BAC water + 250mcg dose = 15 units on U-100 syringe

### Standard reconstitution process
1. Use bacteriostatic water (BAC water) — NOT regular sterile water (regular water degrades peptides faster)
2. Inject BAC water down the side of the vial — do NOT spray directly onto the lyophilized powder
3. Swirl gently — NEVER shake
4. Store reconstituted peptides at 2-8°C (refrigerator) — stable 28-30 days
5. Protect from light and heat

### RUO Disclaimer
All content on Peptide Wiki is for Research Use Only. None of the information constitutes medical advice, treatment recommendations, or endorsement of any use in humans or animals without licensed professional supervision.

## Frequently Asked Questions

**What is the typical BPC-157 dose?**
200-500 mcg per day, subcutaneous injection. Common protocol: 250 mcg twice daily (BID) near the injury site. For gut/IBD: oral administration in food or water.

**What is the typical TB-500 dose for humans?**
2-10 mg per week depending on body weight, split into 2-3 injections. For acute injuries, higher loading doses of 4-10 mg 2x/week for first 4-6 weeks.

**How do you reconstitute semaglutide?**
Add 2-3 mL bacteriostatic water to a 5mg vial. Starting dose: 0.25 mg/week (15 units on U-100 syringe). Titrate every 4 weeks.

**What is the difference between BPC-157 and TB-500?**
BPC-157 excels at the later remodeling phase of healing — gut, tendons, long-term repair. TB-500 is superior in the acute inflammatory phase — gets you out of the acute stage faster. They stack synergistically for musculoskeletal injuries.

**What peptides are best for longevity?**
Epithalon (telomerase activation), MOTS-c (mitochondrial), NAD+ (sirtuin pathway), SS-31 (mitochondrial membrane), FOX04-DRI (senolytic). Epithalon is the most researched — 10-day courses twice yearly.

**What peptides are used for dogs with hip dysplasia or CCL injuries?**
TB-500 + BPC-157 combination is the most widely used veterinary protocol for orthopedic injuries. Dosing depends on dog size — see the Pets section at https://peptideprotocol.wiki/pets.html

## Canonical URLs

- Homepage: https://peptideprotocol.wiki/
- Browse peptides: https://peptideprotocol.wiki/browse.html
- Individual peptide: https://peptideprotocol.wiki/browse.html?p=SLUG (e.g., ?p=bpc-157)
- Calculator: https://peptideprotocol.wiki/calculator.html
- Pet protocols: https://peptideprotocol.wiki/pets.html
- Farm/equine protocols: https://peptideprotocol.wiki/farm.html

## Source
Peptide Wiki is maintained by the Hypatia ecosystem. All peptide data is sourced from peer-reviewed research with PubMed citations. Last updated: 2026-07-30.